STRs database » FXN locus
|Number of repeats||Counts (alleles)||Percentage|
Overview of repeats
Friedreich ataxia (FRDA) is caused by GAA repeat expansions in intron 1 of the FXN gene, with pathogenic repeats ranges from 70 repeats to more than 1000 (most often between 600-900) (Pandolfo, 2001). In healthy individuals, the range is found to be 5-30 GAA repeats (Pandolfo, 2001).