STRipy is a free and open source application created for genotyping short tandem repeats in the simplest way. It allows the genotyping of any STR locus in an aligned Illumina WGS/WES or targeted sequencing file. STRipy also detects whether an allele is in the pathogenic range for 58 diseases caused by 55 loci in 52 genes and provides the distributions of alleles in healthy populations (including the reference missing XYLT1 locus). Information acquired from the literature and in-house population analysis is available on STRipy's STRs database. Additionally, a separate version of STRipy (STRipy-pipeline) is available for a large scale analysis of STRs. More information is available on the About page and the publication.
STRipy's paper has been accepted by Human Mutation and is now published at https://dx.doi.org/10.1002/humu.24382 with free full text access. 🎉🎉
We have released STRipy v2.0. Custom coordinates and motifs can be now used which enables to genotype any locus. This allows to genotype not only STR loci, but also shorter VNTRs as well, such as CSTB, EIF4A3, PRNP and VWA1.
Moreover, coverage on reference is calculated and displayed as a graph (click "Show coverage on ref." link at the left bottom, under "Metadata").